In studying 4,399 male cancer survivors and 6,458 female cancer survivors compared with 31,042 male cancer-free controls and 33,184 female cancer-free controls who were between 50 and 75 years of age who participated in the Vitamins and Lifestyle study, subjects were evaluated by a 24-page questionnaire. Cancer survivors used similar numbers of supplements as cancer-free controls.
OBJECTIVE: To determine whether an elevated homocysteine level
is an independent risk factor for the development of coronary
heart disease (CHD) to aid the US Preventive Services Task Force
in its evaluation of novel risk factors for incident CHD.
METHODS: Studies of homocysteine and CHD were identified by
searching MEDLINE (1966 through March 2006).
In a study involving fructose-fed male Sprague Dawley rats, administration of alpha-lipoic acid and coenzyme Q10 was found to suppress oxidative and nitrative stress, hyperinsulinemia, and insulin resistance. Rats were divided into 4 groups – Group1 served as a control; Group2 received a regular diet and water ad libitum and fructose; Group3 received alpha-lipoic acid (100 mg/kg/d),