Implantation of bone-marrow stem cells in the heart might be a new method to restore tissue viability after myocardial infarction. We injected up to 1.5×106 autologous AC133+ bone-marrow cells into the infarct border zone in six patients who had had a myocardial infarction and undergone coronary artery bypass grafting. 3–9 months after surgery, all patients were alive and well,
The cartilage, which is mesodermal in origin, provides excellent lubrication and wear characteristics required for continuous gliding motion. It serves to absorb mechanical shock and spread the applied load onto the bony supporting structures below. But its limited capacity for repair can cause severe and progressive disability of the joint, such as osteoarthritis. Osteoarthritis is the leading cause of chronic disability in large developed countries like the United States,
Identifying neural, hormonal, renal, and vascular mechanisms that cause system hypertension has led to the development of diagnostics, drugs, and devices for the results of hypertension during the past many decades. These successes have led to a decrease in the rate of stroke and contributed to the decrease in cardiovascular disease in the general population.
Background and Purpose
Adult stem cell is an experimental stroke results. Here, we assessed homing and anti-inflammatory effects of bone marrow stromal cells (hBMSCs) in chronic stroke.
At 60 days post stroke, adult Sprague–Dawley rats received intravenous hBMSCs (4×106 labeled or nonlabeled cells) or vehicle (saline).
Stem cell can promote good recovery from stroke. Several studies have demonstrated that mesenchymal stem cells (MSC) are safe and effective. However, more information regarding appropriate cell type is needed from animal model. This study was targeted at analyzing the effects in ischemic stroke of acute intravenous (i.v.) administration of allogenic bone marrow- (BM-MSC) and adipose-derived-stem cells (AD-MSC) on functional evaluation results and brain repair markers.