In a study involving fructose-fed male Sprague Dawley rats, administration of alpha-lipoic acid and coenzyme Q10 was found to suppress oxidative and nitrative stress, hyperinsulinemia, and insulin resistance. Rats were divided into 4 groups – Group1 served as a control; Group2 received a regular diet and water ad libitum and fructose; Group3 received alpha-lipoic acid (100 mg/kg/d), i.p., for 5 weeks, and Group4 received coenzyme Q10 (10 mg/kg/d), i.p., for 5 weeks. Rats fed a high-fructose diet were found to have significant elevations in plasma LDL, VLDL, and total cholesterol, as well as plasma asymmetric dimethylarginine, malondialdehyde, and glutathione, while showing a decrease in HDL cholesterol. Administration of alpha-lipoic acid and coenzyme Q10 was found to notably suppress oxidative stress, nitrative stress, hyperinsulinemia, and insulin resistance. These results in animals suggest that coenzyme Q10 and alpha-lipoic acid may have a positive effect on markers of the metabolic syndrome. Additional research is warranted.
How Stem Cell Therapy Rejuvenates Hair Follicles and Promotes Growth
Hair thinning and hair loss often happen when follicles are no longer functioning at their best. Some follicles may slow
