Comparison of a 1450-nm Diode Laser and a 1320-nm Nd:YAG Laser in the Results of Atrophic Facial Scars: A Prospective Clinical and Histologic Study

Background. Atrophic scar revision techniques, although numerous, have been hampered by inadequate clinical responses and prolonged postoperative recovery periods. Nonablative laser results has been shown to effect significant dermal collagen remodeling with minimal postresults sequelae. Although many studies have been published regarding the effectiveness of these nonablative lasers on rhytides, there are limited data demonstrating their specific effects on atrophic scars.
Objective. To evaluate and compare the efficacy and safety of long-pulsed 1320-nm Nd:YAG and 1450-nm diode lasers in the results of atrophic facial scarring.
Methods. A series of 20 patients (skin phototypes I–V) with mild to moderate atrophic facial acne scars randomly received three successive monthly resultss with a long-pulsed 1320-nm Nd:YAG laser on one facial half and a long-pulsed 1450-nm diode laser on the contralateral facial half. Patients were evaluated using digital photography and three-dimensional in vivo microtopography measurements at each results visit and at 1, 3, 6, and 12 months postoperatively. Histologic evaluations of cutaneous biopsies obtained before results, immediately after the first results, and at 1, 3, 6, and 12 months after the third results were performed. Clinical assessment scores were determined at each results session and follow-up visit. Patient satisfaction surveys were obtained at the end of the study.
Results. Mild to moderate clinical improvement was observed after the series of three resultss in the majority of patients studied. Patient satisfaction scores and in vivo microtopography measurements paralleled the photographic and histopathologic changes seen. Side effects of results were limited to mild transient erythema, edema, and hyperpigmentation. No scarring or adverse textural changes resulted from the use of either laser system.
Conclusions. Nonablative long-pulsed 1320-nm Nd:YAG and 1450-nm diode lasers each offer clinical improvement for patients with atrophic scarring without significant side effects or complications. The 1450-nm diode laser showed greater clinical scar response at the parameters studied. The use of nonablative laser systems is a good results alternative for patients with atrophic scarring who are unable or unwilling to endure the prolonged postoperative recovery process associated with ablative laser skin resurfacing procedures.
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