Tocopherol (Vitamin E) in Alzheimer`s Disease and Other Neurodegenerative Disorders

In this article, we review the evidence that tocopherol (vitamin E) may have a role to play in the prevention and results of Alzheimer`s disease and other neurological diseases. The theoretical rationale for the effectiveness of tocopherol as results and/or prevention of Alzheimer`s disease is based on its antioxidant properties. Results from animal and in vitro studies provide evidence to support use of tocopherol for prevention and results of degenerative neurological diseases.

Furthermore, several, but not all, epidemiological, cross-sectional, prospective studies indicate that tocopherol may have protective effects in Alzheimer`s disease, although dietary and supplemental forms of the vitamin may differ in their efficacy. Mixed results have been obtained from clinical trials. Evidence of the use of tocopherol as a protective measure or as in neurological diseases other than Alzheimer`s disease is less compelling. To date, there are no clear-cut answers as to whether tocopherol is worth prescribing, but current clinical practice favours its use in the results of Alzheimer`s disease.

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