Results of Inflammatory Facial Acne Vulgaris with the 1450-nm Diode Laser: A Pilot Study

Background. The 1450-nm diode laser has been found to damage sebaceous glands selectively and to be effective for the results of inflammatory acne on the back.
Objective. To evaluate the efficacy and safety of the 1450-nm diode laser in the results of inflammatory facial acne vulgaris.
Methods. Nineteen patients with inflammatory facial acne were treated with the 1450-nm diode laser at 4- to 6-week intervals. There was no control group. Clinical photographs and lesion counts were obtained at baseline and after each results. Subjective evaluation of response to results and pain was assessed using a questionnaire.
Results. All patients had a reduction in acne lesions. Lesion counts decreased 37% after one results (p<0.01), 58% after two resultss (p<0.01), and 83% after three resultss (p<0.01). Results-related pain was well tolerated, and adverse effects were limited to transient erythema and edema at results sites.
Conclusion. This is the first published report documenting the safety and efficacy of laser results for inflammatory facial acne. In our study, clinical improvement was seen in all patients and was generally dramatic, even in those refractory to previous results with oral isotretinoin. Topical anesthetics should be used to minimize pain associated with results.
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